The people we know will make different choices. We will likely agree with some of those choices and disagree with others. Yet, as my mom says, "Let people live their own lives." I would change that statement to "Let people live their own lives as long as they are not hurting others." Often in my life, people's different choices have created a crossroads in relationships. At these crossroads I had to decide whether to speak up or not. At times colleagues would display signange that I felt was dehumanizing, I spoke up and that had a challenging affect on our professional relationship. Looking back, it was probably more about how I spoke up than my actual message, but at the time, I didn't know how to relay a challenging message like that well.
Amongst friends, the difficult conversations have been related to political choices and outlooks. It's very difficult to accept differing political choices if those choices affect the health, safety, and good living of people. We see this differential dramatically in today's political landscape.
With family, the critical differences focused on how we live our lives with regard to how we care for our loved ones, spend our money, and use our time.
In general, most people that I know live good lives dedicated to doing what they can to love and care for others. Amongst those people there's differences on the jobs they do, the families they have, the vacations they take, the homes they live in, the shows they watch, and more. That differential adds interest to our relationships and we learn from one another.
People will make different choices, and as much as possible we have to respect and be curious about those differences as long as their choices are not harming or hurting others.