It's difficult to help a loved one rise from a low time, and it's difficult to raise ourselves from low times too, but there are many avenues one can take in order to rise.
Health?
If you're low and cannot rise, the first consideration should be your health. Is there a health reason that's keeping you low? Get a check-up and eliminate or identify any health reasons for your challenge.
What do you want?
Spend some time dreaming--what is it that you really want? Be willing to visualize yourself in lots of different life ways and think about what appeals to you. Allow yourself to entertain your wildest dreams as that will point to what's missing in your life and what you really want. Then read and research ways to approach your most important dreams. This may signal that it's time to move, change jobs, make new friends, engage in a new hobby or more.
Get some help
Too many people still resist counseling when counseling offers you a great path to betterment. The key here is to find a good counselor. Sometimes that may take a few tries. Start by asking your physician for references, then sign up for a session.
Identify mentors
Identify people who are living the life you want. Think of those people as mentors. Watch what they do. Ask them questions. Follow their lead. It's likely that you'll want to identify a few mentors for different areas of your life.
Consider your enemies
It's possible that you've identified some people as enemies and it could be that those people are your enemies because they have what you want. It also could be true that those people are working against your good living. Identify why people are your enemies, and if they have what you want, reflect on that deeply as it may unlock your challenge in some ways.
Be courageous, try something new
Sometimes we reach low points because we employ the same old, same old pattern without trying anything new. To break a bad cycle, we have to drum up the courage to try something new.
Adopt positivity
The truth that we get what we give is an important consideration. If we're negative all the time, we'll attract negativity, and if we're positive, we'll likely attract a lot of positivity. So trying to be as positive as possible can help.
Be good to yourself
Too many of us beat ourselves up all the time. Treat yourself with the love and care you deserve--figure out how to do that and make that a regular part of your routine.
No one likes to be at a low point, but we all experience that from time to time. It's important to do what we can to navigate out of those holes. Onward.