Our friendships often change when our individual and group directions change. This can sometimes be painful. Once after a painful illness, a friend's life changed dramatically which impacted our friendship. Looking back there were probably actions I could have taken to keep the relationship going, but at the time, my own life was incredibly busy so I missed that opportunity. Our lives took different directions which essentially ended our friendship. I hate to see good friendships end, but sometimes without intention, that happens and when that happens, we can try to make amends which may or may not help.
In general, I think it's good to take time to reflect on changing directions when that happens and then make the kinds of changes that protect a good relationship. For example, my young adult children's lives are changing a lot these days. I want to be cognizant of those changes, and make the kinds of changes in our routines and events that maintain strong, close relationships.
The same is true for the lives of my many siblings, aunts, dad, nieces, nephews, and cousins--their lives are constantly changing, and those changes affect our connections too. I want to be cognizant of that.
What's most important is to recognize the relationships that matter to you and to make the kinds of decisions that protect and develop those relationships with strength and care. Onward.